Ghana have been dealt another big blow with the withdrawal of SC Paderborn winger Christopher Antwi-Adjei and Mohammed Salisu of Real Villadolid.
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Mohammed Salisu has pulled out from the Black Stars squad to face South Africa and São Tome and Principe due to injury.
Kyfilla.com earlier reported that, the 20-year old centre-back will not be available for the double-header after sustaining an injury in Real Villadolid league match against Deportivo Alaves.
Latest to join the list is SC Paderborn winger Christopher Antwi-Adjei who was hoping to make his debut for the Black Stars in the double-header.
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According to report in the media, Antwi-Adjei will not be available for the games due to passport difficulties.
He was expected to travel down to Ghana for the South Africa and São Tome and Principe showdowns but difficulties in securing his Ghanaian passport means he will not be available for the two games.
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The duo have joined Harrison Afful and Mubarak Wakaso who have also pulled out due to unfortunate injury situations.
Ghana take on South Africa in the 2021 AFCON qualifiers at the Cape Coast Sports Stadium on Thursday, November 14, 2019 before traveling to São Tome and Principe to face them on November 18, 2019.